What is the difference between SGOT and AST?

SGOT and AST are two names for the same blood test. AST stands for aspartate aminotransferase.

Is fasting required for AST and ALT tests?

Fasting is usually not required for AST and ALT alone, but follow the laboratory instructions if other tests are being done at the same time.

AST (SGOT) & ALT (SGPT) Tests: Why They're Done and How to Prepare

Introduction

AST and ALT are common liver health blood tests

AST and ALT, also known as SGOT and SGPT, are common blood tests used to assess liver health. Many patients see these names on reports but are unsure why they are done, whether both are needed, or how to prepare.

This guide explains the basics in a simple, practical way.

Basics

What are AST and ALT?

ALT, also called SGPT or alanine aminotransferase, is more specific to the liver. AST, also called SGOT or aspartate aminotransferase, is found in the liver, muscles, and heart.

Test name	Also called	Where it is found
ALT	SGPT	More specific to liver cells
AST	SGOT	Liver, muscle, and heart cells

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AST and ALT are enzymes inside cells. When cells are damaged, these enzymes can leak into the blood.

Uses

Why are AST and ALT tests done?

Doctors commonly request AST and ALT when they want to assess possible liver irritation or injury, especially as part of a broader liver function test.

Suspected liver disease
Fatty liver evaluation
Routine health check-ups
Monitoring medications that may affect the liver
Alcohol-related health concerns

AST and ALT Together

Are both tests always needed?

Usually, AST and ALT are done together. Sometimes only one may be requested, depending on the clinical situation.

Most commonly, they are included in a liver function test, often called an LFT or liver profile. If AST and ALT are already included in that profile, there is usually no need to repeat them separately unless your doctor asks.

Preparation

How is the test done, and do you need to fast?

AST and ALT are checked with a simple blood test. Blood is drawn from a vein, and the sample collection usually takes only a few minutes.

Simple blood test

Blood drawn from a vein

Usually takes only a few minutes

Usually fasting is not required

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Fasting is usually not required for AST and ALT alone. However, some laboratories combine these with other tests, so always follow the instructions given by your lab or doctor.

Results

How long do results take, and how do they appear?

Results are usually available on the same day or the next day, depending on the laboratory.

Example report item	Example value
AST (SGOT)	35 U/L
ALT (SGPT)	42 U/L

Values are shown with a laboratory reference range. The exact range can vary slightly between laboratories.

Interpretation

Do AST and ALT diagnose disease by themselves?

No. AST and ALT alone do not give a final diagnosis. They can indicate possible liver injury or cell damage, but the numbers need to be interpreted with symptoms, examination findings, medication history, alcohol history, other blood tests, and sometimes imaging.

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Interpretation is more important than the numbers alone. Discuss abnormal results with your doctor, especially if values are high or symptoms are present.

Related Guides

Frequently asked questions about AST and ALT tests

They are the same test with different names. AST stands for aspartate aminotransferase, and SGOT is the older name.

Usually yes. AST and ALT are commonly checked together, often as part of a liver function test or liver profile.

Usually no. Fasting is not normally required for AST and ALT alone, but follow lab instructions if other tests are being done at the same time.

Conclusion

AST and ALT help assess liver health

AST (SGOT) and ALT (SGPT) are simple blood tests that help assess liver health. They are easy to perform, widely used, and often included in routine evaluation.

The key point is that interpretation matters more than the numbers alone.

AST (SGOT) & ALT (SGPT) Tests